Search results for " gamma"
showing 10 items of 1276 documents
Responses of European lobster (Homarus gammarus) and lobster fishers to protective management
2017
Master's thesis Aquatic Ecology BIO500 - University of Agder 2017 Marine protected areas (MPAs) are valued for their conservation benefits to harvested species. However, potential benefits of MPAs to neighboring fisheries are less well-understood. This study quantifies how the European lobster (Homarus gammarus) and the fishery for this valued catch respond to the establishment of a relatively small (5.2 km2) MPA on the Norwegian Skagerrak coast. A series of yearly standardized trap surveys was conducted to estimate lobster abundance and catch weights both inside and outside the MPA before (2010- 2011) and after the MPA was established (2012-2016). Lobster abundance and catch weights were d…
CONSTRUCTION OF METASTABLE STATES IN QUANTUM ELECTRODYNAMICS
2004
In this paper, we construct metastable states of atoms interacting with the quantized radiation field. These states emerge from the excited bound states of the non-interacting system. We prove that these states obey an exponential time-decay law. In detail, we show that their decay is given by an exponential function in time, predicted by Fermi's Golden Rule, plus a small remainder term. The latter is proportional to the (4+β)th power of the coupling constant and decays algebraically in time. As a result, though it is small, it dominates the decay for large times. A central point of the paper is that our remainder term is significantly smaller than the one previously obtained in [1] and as…
Association between Serum Heat Shock Proteins and Gamma-Delta T Cells—An Outdated Clue or a New Direction in Searching for an Anticancer Strategy? A …
2021
HSPs demonstrate a strong association with gamma-delta (γδ) T cells. Most of the studies regarding interactions between the parameters were conducted in the 1990s. Despite promising results, the concept of targeting γδ T cells by HSPs seems to be a forgotten direction due to potent non-peptidic phosphoantigens rather than HSPs have been found to be the essential stimulatory components for human γδ cells. Currently, with greater knowledge of lymphocyte diversity, and more accurate diagnostic methods, we decided to study the correlation once again in the neoplastic condition. Twenty-one children with newly diagnosed acute lymphoblastic leukaemia (ALL) were enrolled on the study. Serum HSP90 c…
Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver
1992
AbstractThe process of peroxisome proliferation in rodent liver by hypolipidemic compounds and related substances has recently been shown to be receptor-madiated. In the present study, we have examined the effect of oral administration of the strong peroxisome proliferator fenofibrate on the hepatic expression level of the peroxisome proliferator activated receptor (PPAR) in rats. Immunoblots of rat liver cytosols and nuclear extracs using antibodies raised against recombinant PPAR/β-galactosidase fusion proteins revealed a pronounced increase in the amount of PPAR protein in response to fenofibrate treatment. This induction could also be confirmed at the level or RNA by Northern blotting. …
In Vitro Cytokine Production by HLA-B8, DR3 Positive Subjects
1994
It is well known that healthy subjects carrying the HLA-B8,DR3 haplotype may show an impairment of immune system, the T cells being the most affected. To gain insight into the mechanism(s) of the impairment displayed by these subjects, efforts have been centered on the study of in vitro cytokine production because of the pivotal role played by these mediators in the activation and control of several immune functions. The available results indicate that the ability to several immune functions. The available results indicate that the ability to produce interleukin-1 (IL-1), IL-2 and the soluble form of its receptor (sIL-2R) is impaired in HLA-B8,DR3 positive healthy subjects. To better charac…
High energy neutrinos from novae in symbiotic binaries: The case of V407 Cygni
2010
Detection of high-energy (>= 100 MeV) gamma rays by the Fermi Large Area Telescope from a nova in the symbiotic binary system V407 Cygni has opened the possibility of high-energy neutrino detection from this type of source. A thermonuclear explosion on the white dwarf surface sets off a nova shell in motion that expands and slows down in a dense surrounding medium provided by the red giant companion. Particles are accelerated in the shocks of the shell and interact with the surrounding medium to produce observed gamma rays. We show that proton-proton interaction, which is most likely responsible for producing gamma rays via neutral pion decay, produces >= 0:1 GeV neutrinos that can be detec…
On the importance of background subtraction in the analysis of coronal loops observed with TRACE
2010
In the framework of TRACE coronal observations, we compare the analysis and diagnostics of a loop after subtracting the background with two different and independent methods. The dataset includes sequences of images in the 171 A, 195 A filter bands of TRACE. One background subtraction method consists in taking as background values those obtained from interpolation between concentric strips around the analyzed loop. The other method is a pixel-to-pixel subtraction of the final image when the loop had completely faded out, already used by Reale & Ciaravella 2006. We compare the emission distributions along the loop obtained with the two methods and find that they are considerably differen…
Editorial: Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications.
2020
Introduction: gd T cells have been characterized by the expression of a gd T cell receptor (TCR).When the gd TCR and the corresponding ab TCR were first discovered it was assumed that the corresponding cell types were likely to be functionally very similar. However, some 30 years later, we have realized that they are not. Unlike ab T cells, gd T cells (i) sense target antigens independent of MHC molecules; (ii) display NK-cell like innate reactivities, including killing of infected cells as well as microbes; (iii) are able to take up large particulates, including bacteria, and (iv) can act as professional antigen presenting cells. The “stress sensing” abilities of gd T cells have led to a g…
Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition.
2011
The combined pharmacological approach to the treatment of HIV infection, known as highly active antiretroviral therapy (HAART), has dramatically reduced AIDS-related morbidity and mortality. However, its use has been associated with serious adverse reactions, of which those resulting from mitochondrial dysfunction are particularly widespread. Nucleos(t)ide-reverse transcriptase inhibitors (NRTIs) have long been considered the main source of HAART-related mitochondrial toxicity due to their ability to inhibit Pol-γ, the DNA polymerase responsible for the synthesis of mitochondrial DNA. Nevertheless, accumulating evidence points to a more complex relationship between these organelles and NRTI…
Evaluation of the Spectroscopic Performance of 3D CZT Drift Strip Detectors
2021
CdTe/CZT is an attractive and consolidated material with which to realize detectors with good efficiency and energy resolution, operating at room temperature and suitable for a large variety of applications such as medical imaging, nuclear security, and astrophysics. Right in this last field several spectro-imagers based on these CdTe/CZT detectors were mounted onboard space missions such as INTEGRAL, Swift, and NuSTAR for hard X and gamma-ray astrophysics. Much effort has been expended in the development of CZT spectroscopic imagers for obtaining sub-millimeter spatial resolution in three dimensions (3D) and high energy resolution up to 1 MeV. The motivations are mainly related to the poss…